MCL-1 抗体 (AA 191-226)
(4 references)-
- 抗原 See all MCL-1 (MCL1) 抗体
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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抗原表位
- AA 191-226
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCL-1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1.
- 克隆位点
- RB00961
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MCL1 Primary Antibody
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anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 2-307) antibody
MCL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Center) antibodyMCL1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 1-350) antibodyMCL1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibodyMCL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, IP, ICC 宿主: 兔 Monoclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 19-244) antibodyMCL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 120-220) antibodyMCL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibodyMCL1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 8C6D4B1 unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 191-226) antibodyMCL1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (AA 6-328) antibodyMCL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibodyMCL1 适用: 人, 犬, 猴, Pig, 兔, 豚鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).
: "P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells." in: Apoptosis : an international journal on programmed cell death, Vol. 16, Issue 5, pp. 524-35, (2011) (PubMed).
: "Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia." in: Blood, Vol. 108, Issue 4, pp. 1334-8, (2006) (PubMed).
: "Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 9, pp. 3312-7, (2005) (PubMed).
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: "DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5639-49, (2012) (PubMed).
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- 抗原
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
- 别名
- MCL1 (MCL1 产品)
- 别名
- BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody
- 背景
- The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
- 分子量
- 37337
- 基因ID
- 4170
- NCBI登录号
- NP_001184249, NP_068779, NP_877495
- UniProt
- Q07820
- 途径
- MAPK Pathway
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