This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids of Drosophila SUMO.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
Maarifi, Hannoun, Geoffroy, El Asmi, Zarrouk, Nisole, Blondel, Chelbi-Alix: "MxA Mediates SUMO-Induced Resistance to Vesicular Stomatitis Virus." in: Journal of virology, Vol. 90, Issue 14, pp. 6598-6610, (2017) (PubMed).
Kearse, Ireland, Prem, Chen, Ware: "RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes." in: Nucleus (Austin, Tex.), Vol. 4, Issue 3, pp. 241-58, (2013) (PubMed).
Sahota, Grau, Mansilla, Ferrús: "Troponin I and Tropomyosin regulate chromosomal stability and cell polarity." in: Journal of cell science, Vol. 122, Issue Pt 15, pp. 2623-31, (2009) (PubMed).
抗原
Drosophila SUMO
背景
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.