SUMO2 抗体 (C-Term)
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- 抗原 See all SUMO2 抗体
- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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抗原表位
- AA 63-93, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUMO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- X, Zf, B, C, Ha, Pr, M, Pig, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the C-terminal region of human SUMO2.
- 克隆位点
- RB2761
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SUMO2 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 5, pp. 441-447, (2017) (PubMed).
: "Ubiquitin-related proteins in neuronal and glial intranuclear inclusions in intranuclear inclusion body disease." in: Pathology international, Vol. 62, Issue 6, pp. 407-11, (2012) (PubMed).
: "Incipient intranuclear inclusion body disease in a 78-year-old woman." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 31, Issue 2, pp. 188-93, (2011) (PubMed).
: "SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7." in: Human molecular genetics, Vol. 19, Issue 1, pp. 181-95, (2009) (PubMed).
: "Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies." in: The Journal of cell biology, Vol. 182, Issue 1, pp. 35-9, (2008) (PubMed).
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Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 5, pp. 441-447, (2017) (PubMed).
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- 抗原
- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
- 别名
- SUMO2 (SUMO2 产品)
- 别名
- HSMT3 antibody, SMT3B antibody, SMT3H2 antibody, SUMO3 antibody, Smt3A antibody, SMT3A antibody, SMT3H1 antibody, SUMO-3 antibody, Smt3B antibody, Smt3h2 antibody, sumo2 antibody, zgc:92241 antibody, SUMO2 antibody, SUMO-2 antibody, Smt3b antibody, hsmt3 antibody, smt3b antibody, smt3h2 antibody, sumo-2 antibody, PSMT3 antibody, ATSUMO2 antibody, MCO15.11 antibody, MCO15_11 antibody, SMALL UBIQUITIN-LIKE MODIFIER 2 antibody, SUM2 antibody, SUMO 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 3 antibody, small ubiquitin-like modifier 2b antibody, small ubiquitin-related modifier 2 antibody, small ubiquitin-like modifier 2 S homeolog antibody, small ubiquitin-like modifier 2 L homeolog antibody, SUMO2 antibody, SUMO3 antibody, Sumo2 antibody, sumo2b antibody, LOC714892 antibody, sumo2.S antibody, sumo2.L antibody
- 背景
- SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
- 分子量
- 10871
- 基因ID
- 6613
- NCBI登录号
- NP_001005849, NP_008868
- UniProt
- P61956
- 途径
- Methionine Biosynthetic Process
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