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- 抗原 See all CBLC 抗体
- CBLC (Cbl proto-oncogene C (CBLC))
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抗原表位
- AA 424-453, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBLC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This CBLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-453 amino acids from the C-terminal region of human CBLC.
- 克隆位点
- RB0696
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CBLC Primary Antibody
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anti-Cbl proto-oncogene C (CBLC) (AA 245-474) antibody
CBLC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 245-474) antibodyCBLC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-474) antibodyCBLC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 244-474) antibodyCBLC 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-474) antibodyCBLC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 244-474) antibodyCBLC 适用: 人 WB 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Cbl proto-oncogene C (CBLC) (AA 1-30), (N-Term) antibodyCBLC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0694 unconjugated
anti-Cbl proto-oncogene C (CBLC) antibodyCBLC 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (N-Term) antibodyCBLC 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cbl proto-oncogene C (CBLC) (C-Term) antibodyCBLC 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- CBLC (Cbl proto-oncogene C (CBLC))
- 别名
- CBLC (CBLC 产品)
- 别名
- CBL-3 antibody, CBL-SL antibody, RNF57 antibody, Cbl proto-oncogene C antibody, CBLC antibody, Cblc antibody
- 背景
- Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.
- 分子量
- 52456
- 基因ID
- 23624
- NCBI登录号
- NP_001124324, NP_036248
- UniProt
- Q9ULV8
- 途径
- EGFR Signaling Pathway
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