SENP6 抗体 (C-Term)
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- 抗原 See all SENP6 抗体
- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
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抗原表位
- AA 1081-1112, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SENP6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 amino acids from the C-terminal region of human SENP6.
- 克隆位点
- RB0664
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SENP6 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage." in: The EMBO journal, Vol. 31, Issue 23, pp. 4441-52, (2012) (PubMed).
: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
: "Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30669-77, (2006) (PubMed).
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SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage." in: The EMBO journal, Vol. 31, Issue 23, pp. 4441-52, (2012) (PubMed).
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- 抗原
- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
- 别名
- SENP6 (SENP6 产品)
- 别名
- SSP1 antibody, SUSP1 antibody, 2810017C20Rik antibody, E130319N12Rik antibody, Susp1 antibody, mKIAA0797 antibody, fc83h02 antibody, im:7148342 antibody, wu:fc83h02 antibody, zgc:171230 antibody, SUMO1/sentrin specific peptidase 6 antibody, SUMO/sentrin specific peptidase 6 antibody, SUMO1/sentrin specific peptidase 6a antibody, SENP6 antibody, Senp6 antibody, senp6a antibody
- 背景
- SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.
- 分子量
- 126146
- 基因ID
- 26054
- NCBI登录号
- NP_001093879, NP_056386
- UniProt
- Q9GZR1
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