SENP1 抗体 (C-Term)
-
- 抗原 See all SENP1 抗体
- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
-
抗原表位
- AA 560-590, C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SENP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 预测反应
- M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-590 amino acids from the C-terminal region of human SENP1.
- 克隆位点
- RB00649-RB0650
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SENP1 Primary Antibody
-
-
- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
-
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 19288-95, (2013) (PubMed).
: "Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5073-8, (2007) (PubMed).
: "
-
Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 19288-95, (2013) (PubMed).
-
- 抗原
- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
- 别名
- SENP1 (SENP1 产品)
- 别名
- SuPr-2 antibody, 2310046A20Rik antibody, D15Ertd528e antibody, E330036L07Rik antibody, suPr-2 antibody, senp1 antibody, senp1a antibody, xsenp1 antibody, SENP1 antibody, Senp1 antibody, senp1b antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific peptidase 1 S homeolog antibody, sentrin/SUMO-specific protease 1 antibody, SUMO1/sentrin specific peptidase 1 L homeolog antibody, SENP1 antibody, Senp1 antibody, senp1.S antibody, senp1.L antibody, senp1 antibody
- 背景
- SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
- 分子量
- 73481
- 基因ID
- 29843
- NCBI登录号
- NP_001254523, NP_001254524
- UniProt
- Q9P0U3
- 途径
- Positive Regulation of Endopeptidase Activity
-