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SENP1 抗体 (N-Term)

SENP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0647 unconjugated
产品编号 ABIN388042
发货至: 中国
  • 抗原 See all SENP1 抗体
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    抗原表位
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 28-59, N-Term
    适用
    • 55
    • 22
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 66
    • 2
    克隆类型
    • 59
    • 9
    多克隆
    标记
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SENP1 antibody is un-conjugated
    应用范围
    • 49
    • 35
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1.
    克隆位点
    RB0647
    亚型
    Ig Fraction
    Top Product
    Discover our top product SENP1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Kim, Choi, Kim, Kim, Lee, Kim, Lee, Choi, Kim, Kim, Chung, Baek: "Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis." in: Nature cell biology, Vol. 8, Issue 6, pp. 631-9, (2006) (PubMed).

    Chen, Chen: "MDM2-ARF complex regulates p53 sumoylation." in: Oncogene, Vol. 22, Issue 34, pp. 5348-57, (2003) (PubMed).

  • 抗原
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    别名
    SENP1 (SENP1 产品)
    别名
    SuPr-2 antibody, 2310046A20Rik antibody, D15Ertd528e antibody, E330036L07Rik antibody, suPr-2 antibody, senp1 antibody, senp1a antibody, xsenp1 antibody, SENP1 antibody, Senp1 antibody, senp1b antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific peptidase 1 S homeolog antibody, sentrin/SUMO-specific protease 1 antibody, SUMO1/sentrin specific peptidase 1 L homeolog antibody, SENP1 antibody, Senp1 antibody, senp1.S antibody, senp1.L antibody, senp1 antibody
    背景
    SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
    分子量
    73481
    基因ID
    29843
    NCBI登录号
    NP_001254523, NP_001254524
    UniProt
    Q9P0U3
    途径
    Positive Regulation of Endopeptidase Activity
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