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SUMO1 抗体 (C-Term)

Name: SUMO1 抗体 (C-Term)
SKU: ABIN388027
Availability: OutOfStock

SUMO1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB0632 unconjugated

The anti-SUMO1 polyclonal antibody (ABIN388027 and ABIN2845493) is used in Western blot to detect GST-SUMO1 fusion protein. (SUMO1 抗体 (C-Term))

SUMO1 Antibody (C-term) (ABIN388027 and ABIN2845493) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (SUMO1 抗体 (C-Term))

FACS

COS-7 cells were transfected for 24 hrs with a plasmid expressing FLAG-ERM (left panels) or FLAG-ERM K (right panels). (SUMO1 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (SUMO1 抗体 (C-Term))

IHC (p)

4 images

(3 references)

产品编号 ABIN388027

发货至: 中国

Datasheet as PDF

抗原 See all SUMO1 抗体

SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
抗原表位
15

15

11

8

7

4

4

3

3

1

1

1

1

1

1

1
AA 55-86, C-Term
适用
94

78

73

5

5

5

4

4

4

3

3

3

2

1

1

1

1

1
人
宿主
98

31

3

1

1
兔
Compatible Secondaries
克隆类型
90

45
多克隆
标记
68

10

7

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This SUMO1 antibody is un-conjugated
应用范围
108

47

46

37

32

27

26

23

16

9

8

7

6

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, M, Pig, Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This SUMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-86 amino acids from the C-terminal region of human SUMO1.

克隆位点

RB0632

亚型

Ig Fraction

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anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibody
SUMO1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人, 大鼠 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal SM1-495 unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (N-Term) antibody
SUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibody
SUMO1 适用: 人 WB, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30), (N-Term) antibody
SUMO1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB0629 unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 52-79) antibody
SUMO1 适用: 人 WB, IF, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30) antibody
SUMO1 适用: 人 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 55-86) antibody
SUMO1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人 IHC, ELISA, FACS, IP 宿主: 兔 Monoclonal 5G3 unconjugated Recombinant Antibody

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Laoong-u-thai, Zhao, Phongdara, Ako, Yang: "Identifications of SUMO-1 cDNA and its expression patterns in Pacific white shrimp Litopeanaeus vannamei." in: International journal of biological sciences, Vol. 5, Issue 2, pp. 205-14, (2009) (PubMed).

Rathke, Baarends, Jayaramaiah-Raja, Bartkuhn, Renkawitz, Renkawitz-Pohl: "Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila." in: Journal of cell science, Vol. 120, Issue Pt 9, pp. 1689-700, (2007) (PubMed).

Degerny, Monte, Beaudoin, Jaffray, Portois, Hay, de Launoit, Baert: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, (2005) (PubMed).
抗原

SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

别名

SUMO1 (SUMO1 产品)

背景

Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

分子量

11557

基因ID

7341

NCBI登录号

NP_001005781, NP_001005782, NP_003343

UniProt

P63165

途径

M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway