This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.
Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.