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HDAC1 抗体 (C-Term)

HDAC1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB5642 unconjugated
产品编号 ABIN387945
发货至: 中国
  • 抗原 See all HDAC1 抗体
    HDAC1 (Histone Deacetylase 1 (HDAC1))
    抗原表位
    • 15
    • 14
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 449-482, C-Term
    适用
    • 138
    • 74
    • 60
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 118
    • 22
    • 2
    克隆类型
    • 117
    • 25
    多克隆
    标记
    • 98
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC1 antibody is un-conjugated
    应用范围
    • 102
    • 74
    • 40
    • 38
    • 26
    • 18
    • 14
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-482 amino acids from the C-terminal region of human HDAC1.
    克隆位点
    RB5642
    亚型
    Ig Fraction
    Top Product
    Discover our top product HDAC1 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).

  • 抗原
    HDAC1 (Histone Deacetylase 1 (HDAC1))
    别名
    HDAC1 (HDAC1 产品)
    背景
    Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
    分子量
    55103
    基因ID
    3065
    NCBI登录号
    NP_004955
    UniProt
    Q13547
    途径
    Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
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