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UBE2I 抗体 (N-Term)

UBE2I 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2811 unconjugated
产品编号 ABIN387910
发货至: 中国
  • 抗原 See all UBE2I 抗体
    UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
    抗原表位
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 70
    • 33
    • 32
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 59
    • 10
    • 2
    克隆类型
    • 52
    • 19
    多克隆
    标记
    • 33
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This UBE2I antibody is un-conjugated
    应用范围
    • 47
    • 29
    • 22
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Zf, C, M, Rat, X
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This UBC9 (UBE2I) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBC9 (UBE2I).
    克隆位点
    RB2811
    亚型
    Ig Fraction
    Top Product
    Discover our top product UBE2I Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lee, Kraus, Prins, Groenendyk, Aubry, Liu, Li, Julien, Touret, Sykes, Tremblay, Michalak: "UBC9-dependent association between calnexin and protein tyrosine phosphatase 1B (PTP1B) at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 290, Issue 9, pp. 5725-38, (2015) (PubMed).

    Fu, Xiong, Xu, Cheng, Tang: "MDA5 is SUMOylated by PIAS2? in the upregulation of type I interferon signaling." in: Molecular immunology, Vol. 48, Issue 4, pp. 415-22, (2011) (PubMed).

  • 抗原
    UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
    别名
    UBC9 (UBE2I) (UBE2I 产品)
    别名
    C358B7.1 antibody, P18 antibody, UBC9 antibody, ubc9 antibody, ube2ia antibody, zUbc9 antibody, 5830467E05Rik antibody, F830028O17Rik antibody, Ubce2i antibody, Ubce9 antibody, UbcE2A antibody, ubce9 antibody, T13J8.70 antibody, T13J8_70 antibody, UBIQUITIN-PROTEIN LIGASE antibody, ubiquitin conjugating enzyme 9 antibody, ubiquitin conjugating enzyme E2 I antibody, ubiquitin-conjugating enzyme E2Ib antibody, ubiquitin-conjugating enzyme E2L antibody, ubiquitin-conjugating enzyme E2I antibody, ubiquitin conjugating enzyme E2I S homeolog antibody, ubiquitin conjugating enzyme 9 antibody, SUMO-conjugating enzyme UBC9 antibody, UBE2I antibody, ube2ib antibody, UBE2L antibody, Ube2i antibody, ube2i.S antibody, UBC9 antibody, ubc-9 antibody, LOC108703134 antibody
    背景
    UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.
    分子量
    18007
    基因ID
    7329
    NCBI登录号
    NP_003336, NP_919235, NP_919236, NP_919237
    UniProt
    P63279
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
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