UBE2I 抗体 (N-Term)
-
- 抗原 See all UBE2I 抗体
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
-
抗原表位
- AA 1-30, N-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This UBE2I antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Zf, C, M, Rat, X
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This UBC9 (UBE2I) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBC9 (UBE2I).
- 克隆位点
- RB2811
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UBE2I Primary Antibody
-
-
- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
-
UBC9-dependent association between calnexin and protein tyrosine phosphatase 1B (PTP1B) at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 290, Issue 9, pp. 5725-38, (2015) (PubMed).
: "MDA5 is SUMOylated by PIAS2? in the upregulation of type I interferon signaling." in: Molecular immunology, Vol. 48, Issue 4, pp. 415-22, (2011) (PubMed).
: "
-
UBC9-dependent association between calnexin and protein tyrosine phosphatase 1B (PTP1B) at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 290, Issue 9, pp. 5725-38, (2015) (PubMed).
-
- 抗原
- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
- 别名
- UBC9 (UBE2I) (UBE2I 产品)
- 别名
- C358B7.1 antibody, P18 antibody, UBC9 antibody, ubc9 antibody, ube2ia antibody, zUbc9 antibody, 5830467E05Rik antibody, F830028O17Rik antibody, Ubce2i antibody, Ubce9 antibody, UbcE2A antibody, ubce9 antibody, T13J8.70 antibody, T13J8_70 antibody, UBIQUITIN-PROTEIN LIGASE antibody, ubiquitin conjugating enzyme 9 antibody, ubiquitin conjugating enzyme E2 I antibody, ubiquitin-conjugating enzyme E2Ib antibody, ubiquitin-conjugating enzyme E2L antibody, ubiquitin-conjugating enzyme E2I antibody, ubiquitin conjugating enzyme E2I S homeolog antibody, ubiquitin conjugating enzyme 9 antibody, SUMO-conjugating enzyme UBC9 antibody, UBE2I antibody, ube2ib antibody, UBE2L antibody, Ube2i antibody, ube2i.S antibody, UBC9 antibody, ubc-9 antibody, LOC108703134 antibody
- 背景
- UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.
- 分子量
- 18007
- 基因ID
- 7329
- NCBI登录号
- NP_003336, NP_919235, NP_919236, NP_919237
- UniProt
- P63279
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
-