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JMJD2D 抗体 (C-Term)

KDM4D 适用: 人 WB 宿主: 兔 Polyclonal RB10797 unconjugated
产品编号 ABIN387871
发货至: 中国
  • 抗原 See all JMJD2D (KDM4D) 抗体
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    抗原表位
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 484-516, C-Term
    适用
    • 33
    • 3
    • 2
    • 1
    宿主
    • 33
    克隆类型
    • 33
    多克隆
    标记
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JMJD2D antibody is un-conjugated
    应用范围
    • 22
    • 18
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This JMJD2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-516 amino acids from the C-terminal region of human JMJD2D.
    克隆位点
    RB10797
    亚型
    Ig Fraction
    Top Product
    Discover our top product KDM4D Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    别名
    JMJD2D (KDM4D 产品)
    别名
    JMJD2D antibody, 4932416A15 antibody, Jmjd2d antibody, KDM4D antibody, lysine demethylase 4D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody, KDM4D antibody, LOC524768 antibody, Kdm4d antibody, LOC617971 antibody, LOC100067461 antibody, LOC698455 antibody, LOC100514356 antibody
    背景
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    分子量
    58603
    基因ID
    55693
    NCBI登录号
    NP_060509
    UniProt
    Q6B0I6
    途径
    Warburg Effect
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