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Kdm6b 抗体 (AA 954-987)

Kdm6b 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB10080 unconjugated
产品编号 ABIN387864
发货至: 中国
  • 抗原 See all Kdm6b 抗体
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    抗原表位
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 954-987
    适用
    • 43
    • 24
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 46
    • 1
    • 1
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 31
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Kdm6b antibody is un-conjugated
    应用范围
    • 36
    • 21
    • 11
    • 6
    • 6
    • 5
    • 3
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Mouse JMJD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 954-987 amino acids from the Central region of mouse JMJD3.
    克隆位点
    RB10080
    亚型
    Ig Fraction
    Top Product
    Discover our top product Kdm6b Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Shaw, Martin: "Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes." in: EMBO reports, Vol. 10, Issue 8, pp. 881-6, (2009) (PubMed).

  • 抗原
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    别名
    JMJD3 (Kdm6b 产品)
    别名
    jmjd3 antibody, kdm6b antibody, si:ch211-237l4.7 antibody, 1700064E03Rik antibody, BC038313 antibody, Jmjd3 antibody, mKIAA0346 antibody, JMJD3 antibody, lysine (K)-specific demethylase 6B antibody, lysine demethylase 6B antibody, lysine (K)-specific demethylase 6B, b antibody, KDM1 lysine (K)-specific demethylase 6B antibody, kdm6b antibody, KDM6B antibody, kdm6bb antibody, Kdm6b antibody
    背景
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    分子量
    176355
    基因ID
    216850
    NCBI登录号
    NP_001017426
    UniProt
    Q5NCY0
    途径
    Warburg Effect
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