Kdm6b 抗体 (C-Term)
(5 references)-
- 抗原 See all Kdm6b 抗体
- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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抗原表位
- AA 1606-1641, C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kdm6b antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- H
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse JMJD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1606-1641 amino acids from the C-terminal region of mouse JMJD3.
- 克隆位点
- RB10081-RB10082
- 亚型
- Ig Fraction
- Top Product
- Discover our top product Kdm6b Primary Antibody
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anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 265-450) antibody
Kdm6b 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30), (N-Term) antibodyKdm6b 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10077 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30) antibodyKdm6b 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1530-1682) antibodyKdm6b 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1023-1057) antibodyKdm6b 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50943 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 879-912) antibodyKdm6b 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51280 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (N-Term) antibodyKdm6b 适用: 人, 大鼠, 犬, 兔, Cow, 马, 猴, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1613-1662) antibodyKdm6b 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1161-1350) antibodyKdm6b 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (Middle Region) antibodyKdm6b 适用: 人, 小鼠, 大鼠, 犬, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- 有效期
- 6 months
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: "Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 2, pp. 902-11, (2013) (PubMed).
: "Gene networking and inflammatory pathway analysis in a JMJD3 knockdown human monocytic cell line." in: Cell biochemistry and function, Vol. 30, Issue 3, pp. 224-32, (2012) (PubMed).
: "p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation." in: PLoS ONE, Vol. 6, Issue 3, pp. e18421, (2011) (PubMed).
: "Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 5, pp. 2130-5, (2011) (PubMed).
: "The role of NF-kappaB and H3K27me3 demethylase, Jmjd3, on the anthrax lethal toxin tolerance of RAW 264.7 cells." in: PLoS ONE, Vol. 5, Issue 3, pp. e9913, (2010) (PubMed).
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: "Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 2, pp. 902-11, (2013) (PubMed).
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- 抗原
- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
- 别名
- JMJD3 (Kdm6b 产品)
- 别名
- jmjd3 antibody, kdm6b antibody, si:ch211-237l4.7 antibody, 1700064E03Rik antibody, BC038313 antibody, Jmjd3 antibody, mKIAA0346 antibody, JMJD3 antibody, lysine (K)-specific demethylase 6B antibody, lysine demethylase 6B antibody, lysine (K)-specific demethylase 6B, b antibody, KDM1 lysine (K)-specific demethylase 6B antibody, kdm6b antibody, KDM6B antibody, kdm6bb antibody, Kdm6b antibody
- 背景
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
- 分子量
- 176355
- 基因ID
- 216850
- NCBI登录号
- NP_001017426
- UniProt
- Q5NCY0
- 途径
- Warburg Effect
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