Nanog 抗体
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- 抗原 See all Nanog (NANOG) 抗体
- Nanog (NANOG) (Nanog Homeobox (NANOG))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Nanog antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This NANOG monoclonal antibody is generated from mouse immunized with NANOG recombinant protein.
- 克隆位点
- 60CT77-1-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product NANOG Primary Antibody
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- 应用备注
- WB: 1:100~250. WB: 1:100~250. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- 别名
- NANOG (NANOG 产品)
- 背景
- Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
- 分子量
- 34620
- 基因ID
- 79923
- NCBI登录号
- NP_079141
- UniProt
- Q9H9S0
- 途径
- Stem Cell Maintenance
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