SUMO1 抗体
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- 抗原 See all SUMO1 抗体
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SUMO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- Purified recombinant GST-SUMO1 fusion protein was used as immunogen.
- 克隆位点
- 66AT1273-94
- 亚型
- IgG1
- Top Product
- Discover our top product SUMO1 Primary Antibody
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- 应用备注
- IF: 1:25. WB: 1:100~500. WB: 1:4000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25. IHC: 1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis." in: The Journal of biological chemistry, Vol. 287, Issue 5, pp. 3231-40, (2012) (PubMed).
: "Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity." in: The Journal of biological chemistry, Vol. 287, Issue 19, pp. 15154-63, (2012) (PubMed).
: "Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 11, pp. 4092-7, (2012) (PubMed).
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Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis." in: The Journal of biological chemistry, Vol. 287, Issue 5, pp. 3231-40, (2012) (PubMed).
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- 抗原
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
- 别名
- SUMO1 (SUMO1 产品)
- 背景
- This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
- 分子量
- 11557
- 基因ID
- 7341
- NCBI登录号
- NP_001005781, NP_001005782, NP_003343
- UniProt
- P63165
- 途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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