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PRDM2 抗体 (AA 1-347)

PRDM2 适用: 人, 小鼠 WB, ChIP 宿主: 小鼠 Monoclonal 33AT1045 unconjugated
产品编号 ABIN387783
发货至: 中国
  • 抗原 See all PRDM2 抗体
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    抗原表位
    • 15
    • 15
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-347
    适用
    • 68
    • 13
    • 11
    人, 小鼠
    宿主
    • 59
    • 11
    小鼠
    克隆类型
    • 60
    • 10
    单克隆
    标记
    • 17
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRDM2 antibody is un-conjugated
    应用范围
    • 39
    • 29
    • 26
    • 26
    • 19
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
    克隆位点
    33AT1045
    亚型
    IgG1
    Top Product
    Discover our top product PRDM2 Primary Antibody
  • 应用备注
    CHIP: 1:100. CHIP: 1:100. CHIP: 1:100. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).

    Carling, Kim, Yang, Gu, Zhang, Huang: "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).

  • 抗原
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    别名
    PRDM2 (RIZ1) (PRDM2 产品)
    别名
    MGC114763 antibody, prdm2 antibody, riz antibody, kmt8 antibody, riz1 antibody, riz2 antibody, mtb-zf antibody, humhoxy1 antibody, PRDM2 antibody, HUMHOXY1 antibody, KMT8 antibody, MTB-ZF antibody, RIZ antibody, RIZ1 antibody, RIZ2 antibody, 4833427P12Rik antibody, E330024L24Rik antibody, Gm1033 antibody, Gm19732 antibody, Riz antibody, Riz1 antibody, Znfpr1c1 antibody, PR domain containing 2, with ZNF domain S homeolog antibody, PR domain containing 2, with ZNF domain b antibody, PR domain containing 2, with ZNF domain antibody, PR domain zinc finger protein 2 antibody, PR/SET domain 2 antibody, prdm2.S antibody, prdm2b antibody, prdm2 antibody, LOC100350859 antibody, PRDM2 antibody, Prdm2 antibody
    背景
    This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    188915
    基因ID
    7799
    NCBI登录号
    NP_001007258, NP_001129082, NP_036363, NP_056950
    UniProt
    Q13029
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