PRDM2 抗体 (AA 1-347)
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- 抗原 See all PRDM2 抗体
- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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抗原表位
- AA 1-347
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRDM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
- 克隆位点
- 33AT1045
- 亚型
- IgG1
- Top Product
- Discover our top product PRDM2 Primary Antibody
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- 应用备注
- CHIP: 1:100. CHIP: 1:100. CHIP: 1:100. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).
: "A histone methyltransferase is required for maximal response to female sex hormones." in: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).
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RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." in: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).
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- 抗原
- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
- 别名
- PRDM2 (RIZ1) (PRDM2 产品)
- 别名
- MGC114763 antibody, prdm2 antibody, riz antibody, kmt8 antibody, riz1 antibody, riz2 antibody, mtb-zf antibody, humhoxy1 antibody, PRDM2 antibody, HUMHOXY1 antibody, KMT8 antibody, MTB-ZF antibody, RIZ antibody, RIZ1 antibody, RIZ2 antibody, 4833427P12Rik antibody, E330024L24Rik antibody, Gm1033 antibody, Gm19732 antibody, Riz antibody, Riz1 antibody, Znfpr1c1 antibody, PR domain containing 2, with ZNF domain S homeolog antibody, PR domain containing 2, with ZNF domain b antibody, PR domain containing 2, with ZNF domain antibody, PR domain zinc finger protein 2 antibody, PR/SET domain 2 antibody, prdm2.S antibody, prdm2b antibody, prdm2 antibody, LOC100350859 antibody, PRDM2 antibody, Prdm2 antibody
- 背景
- This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 188915
- 基因ID
- 7799
- NCBI登录号
- NP_001007258, NP_001129082, NP_036363, NP_056950
- UniProt
- Q13029
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