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ITGAL 抗体

ITGAL 适用: 人 FACS, IP, IHC 宿主: 小鼠 Monoclonal 38 unconjugated
产品编号 ABIN375486
发货至: 中国
  • 抗原 See all ITGAL 抗体
    ITGAL (Integrin alpha-L (ITGAL))
    适用
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    宿主
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    小鼠
    克隆类型
    • 140
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    单克隆
    标记
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    This ITGAL antibody is un-conjugated
    应用范围
    • 131
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    产品特性
    The antibody detects: Human CD11a (LFA-1 α )
    To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.
    纯化方法
    Purified
    内毒素水平
    Low Endotoxin
    克隆位点
    38
    亚型
    IgG2a
    Top Product
    Discover our top product ITGAL Primary Antibody
  • 应用备注
    Working Dilution:
    <= 1 µg/10^6 cells
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    说明

    Blocking studies, cell adhesion, cytotoxicity

    样本量
    1 mL
    限制
    仅限研究用
  • 储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Venet, Ribeiro, Décembre, Bellomo, Joshi, Nuovo, Villard, Cluet, Perret, Pescamona, Paidassi, Walzer, Allatif, Belot, Trouillet-Assant, Ricci, Dreux: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." in: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).

  • 抗原
    ITGAL (Integrin alpha-L (ITGAL))
    别名
    CD11a/LFA-1a (ITGAL 产品)
    别名
    CD11A antibody, LFA-1 antibody, LFA1A antibody, (p180) antibody, Cd11a antibody, LFA-1A antibody, Ly-15 antibody, Ly-21 antibody, CD11a antibody, ITGAL antibody, integrin subunit alpha L antibody, integrin alpha L antibody, ITGAL antibody, Itgal antibody
    背景
    CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 α ), represents the 180 kDa integrin α L subunit which combines with the CD18 β 2 integrin subunit to form the α L β 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 α mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.
    途径
    Activated T Cell Proliferation, Integrin Complex
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