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FTH1 抗体 (C-Term, Heavy Chain)

FTH1 适用: 人, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375067
发货至: 中国
  • 抗原 See all FTH1 抗体
    FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
    抗原表位
    • 16
    • 11
    • 11
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term, Heavy Chain
    适用
    • 76
    • 46
    • 29
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 犬
    宿主
    • 85
    • 10
    • 1
    • 1
    山羊
    克隆类型
    • 80
    • 17
    多克隆
    标记
    • 42
    • 15
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTH1 antibody is un-conjugated
    应用范围
    • 74
    • 39
    • 30
    • 25
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-DKHTLGDSDN ES
    特异性
    This antibody recognizes FTH1 at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Canine.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the C-Terminus of the protein sequence according to NP_002023.2. Genename: FTH1
    Top Product
    Discover our top product FTH1 Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.03-0.1 μg/mL. Approx.22 kDa band observed in Human Brain (Cerebellum),Liver and Placenta lysates. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Sammarco, Ditch, Banerjee, Grabczyk: "Ferritin L and H subunits are differentially regulated on a post-transcriptional level." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4578-87, (2008) (PubMed).

  • 抗原
    FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
    别名
    Ferritin Heavy Chain (FTH1) (FTH1 产品)
    别名
    FHC antibody, FTH antibody, FTHL6 antibody, PIG15 antibody, PLIF antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, fth1b antibody, Fth antibody, HFt antibody, MFH antibody, fb06g09 antibody, hm:zeh1145 antibody, wu:fb06g09 antibody, wu:fq18c10 antibody, zeh1145 antibody, ferritin heavy chain 1 antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin, heavy polypeptide 1 S homeolog antibody, ferritin heavy polypeptide 1 antibody, ferritin, heavy polypeptide 1a antibody, ferritin antibody, ferritin, heavy polypeptide 1 antibody, tudor domain containing 9 antibody, ferritin, heavy polypeptide 1 a antibody, FTH1 antibody, fth1.L antibody, fth1.S antibody, Fth1 antibody, fth1a antibody, EAMY_RS19690 antibody, fth1 antibody, TDRD9 antibody
    背景
    Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: Cell proliferation-inducing gene 15 protein, EC=1.16.3.1, FTH, FTH-1, FTHL6, Ferritin H subunit
    分子量
    21.2kDa (NP_002023.2)
    基因ID
    2495
    NCBI登录号
    NP_002023
    UniProt
    P02794
    途径
    Transition Metal Ion Homeostasis
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