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- 抗原 See all AKR1B10 抗体
- AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This AKR1B10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to AKR1B10.
- 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-QSSHLEDYPFDAE, from the C Terminus of the protein sequence
- Top Product
- Discover our top product AKR1B10 Primary Antibody
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- 应用备注
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Peptide ELISA: 1/8000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity." in: Cancer research, Vol. 71, Issue 12, pp. 4161-71, (2011) (PubMed).
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Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity." in: Cancer research, Vol. 71, Issue 12, pp. 4161-71, (2011) (PubMed).
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- 抗原
- AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))
- 别名
- AKR1B10 (AKR1B10 产品)
- 别名
- AKR1B11 antibody, AKR1B12 antibody, ALDRLn antibody, ARL-1 antibody, ARL1 antibody, HIS antibody, HSI antibody, 2310005E10Rik antibody, Akr1b16 antibody, AKR antibody, AKR1B10 antibody, Akr1b10 antibody, aldo-keto reductase family 1 member B10 antibody, aldo-keto reductase family 1, member B10 (aldose reductase) antibody, aldo-keto reductase family 1 member B10-like 2 antibody, AKR1B10 antibody, Akr1b10 antibody, AKR1B10L2 antibody, LOC100585902 antibody, LOC100723118 antibody, LOC101107697 antibody
- 背景
- ARK1B10 is a NADPH dependant enzyme with an ability to efficiently reduce aliphatic and aromatic aldehydes. A 316 A.A protein, AKR1B10 is a highly efficient retinal reductase constituting the first cytosolic NADP (H) dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications. It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.Synonyms: AKR1B11, ARL-1, Aldo-keto reductase family 1 member B10, Aldose reductase-like, Aldose reductase-related protein, Small intestine reductase
- 基因ID
- 57016, 9606
- UniProt
- O60218
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