GALR2 抗体 (Internal Region)
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- 抗原 See all GALR2 抗体
- GALR2 (Galanin Receptor 2 (GALR2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This GALR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to GALR2.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-RYPLHSRELRTPRN, from the internal region of the protein sequence
- Top Product
- Discover our top product GALR2 Primary Antibody
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anti-Galanin Receptor 2 (GALR2) (AA 51-150) antibody
GALR2 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Transmembrane Domain) antibodyGALR2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (C-Term) antibodyGALR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 282-387) antibodyGALR2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) antibodyGALR2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Internal Region) antibodyVerified GALR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 50-150) antibodyGALR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (3rd Intracellular Loop), (AA 223-235) antibodyGALR2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/4000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- GALR2 (Galanin Receptor 2 (GALR2))
- 别名
- GALR2 (GALR2 产品)
- 背景
- Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30 amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7 transmembrane family of G protein coupled receptors. GALR2 interacts with the N terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.GalR2 expression has been documented widely in the brain and in peripheral tissues including small intestine, heart, kidney, and liver. Localization data from rat CNS indicate high levels of expression in dorsal root ganglia, amygdala and Purkinje neurons.Synonyms: GAL2-R, GALNR2, GALR-2, Galanin receptor type 2
- 基因ID
- 8811
- NCBI登录号
- NP_003848
- UniProt
- O43603
- 途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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