PAX8 抗体 (Internal Region)
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- 抗原 See all PAX8 抗体
- PAX8 (Paired Box 8 (PAX8))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This PAX8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- C-AQPGSDKRKM DD
- 特异性
- This antibody detects PAX8. It is expected to recognise all reported isoforms (NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1).
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from the internal region of the protein sequence according to NP_003457.1, NP_039245.1, NP_039246.1, NP_039247.1, NP_054698.1 Genename: PAX8
- Top Product
- Discover our top product PAX8 Primary Antibody
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anti-Paired Box 8 (PAX8) antibody
KO Validated PAX8 适用: 人 WB, IHC, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal PAX8-1492 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A1D3 unconjugated
anti-Paired Box 8 (PAX8) (AA 1-450) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PAX8-1491 unconjugated
anti-Paired Box 8 (PAX8) (AA 141-250) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Paired Box 8 (PAX8) (N-Term) antibodyVerified PAX8 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 300-450) antibodyPAX8 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3E6B3 unconjugated
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- 应用备注
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.5-1.5 μg/mL. Approx 48 kDa + 48 kDa bands observed in lysates of cell lineHEK293 (calculated MW of 48.8 kDa according to PAX8A, NP_003457.1 and 41.8 kDaaccording to PAX8B, NP_039245.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- 抗原
- PAX8 (Paired Box 8 (PAX8))
- 别名
- PAX8 (PAX8 产品)
- 别名
- PAX8 antibody, XPax-8 antibody, XPax8 antibody, pax-8 antibody, PAX-8 antibody, Pax-8 antibody, paired box 8 antibody, paired box 8 L homeolog antibody, PAX8 antibody, pax8 antibody, Pax8 antibody, pax8.L antibody
- 背景
- This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.Synonyms: Paired box protein Pax-8, Pax-8
- 基因ID
- 7849
- NCBI登录号
- NP_003457
- UniProt
- Q06710
- 途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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