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SHP1 抗体 (C-Term, Internal Region)

Name: SHP1 抗体 (C-Term, Internal Region)
SKU: ABIN374793
Availability: OutOfStock

PTPN6 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated

Image no. 1 for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (C-Term), (Internal Region) antibody (ABIN374793) (SHP1 抗体 (C-Term, Internal Region))

1 image

产品编号 ABIN374793

发货至: 中国

Datasheet as PDF

抗原 See all SHP1 (PTPN6) 抗体

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
抗原表位
34

12

7

6

5

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term, Internal Region
适用
110

64

46

4

2

2

2

2

1

1

1

1
人
宿主
100

12

1
山羊
Compatible Secondaries
克隆类型
93

20
多克隆
标记
55

6

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1
This SHP1 antibody is un-conjugated
应用范围
81

31

23

20

18

14

14

11

11

7

4

3

2

2

1

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

序列

C-HTKNKREEKV KKQ

特异性

This antibody is expected to recognise both reported isoforms of Human PTPN6 (NP_536858.1 and NP_002822.2).

交叉反应（详细）

Species reactivity (tested):Human.

纯化方法

Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

免疫原

Peptide from the internal region (near the C Terminus) of the protein sequence according to NP_536858.1 and NP_002822.2. Genename: PTPN6

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anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人 WB, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) antibody
PTPN6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 243-541) antibody
PTPN6 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2E9E4 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597), (Isoform 2) antibody
PTPN6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (C-Term) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 100-400) antibody
PTPN6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277) antibody
PTPN6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17225 unconjugated

anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Peptide ELISA: antibody detection limit dilution 1: 128000. Western blot: 0.2-0.5 μg/mL. Approx 70 kDa band observed in lysates of cell lines Jurkat andU937 (calculated MW of 67.0 kDa according to NP_536858.1 and 67.0 kDa according toNP_002822.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

别名

PTPN6 (PTPN6 产品)

背景

SHP1 is a member of the non receptor protein tyrosine phosphatase subfamily. The PTP family comprises of at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is cytosolic. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. SHP1 is implicated in the control of tyrosine kinase signalling pathways in cellular proliferation, with a potential role in cancer.Synonyms: HCP, Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, PTP1C, PTPN-6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6

基因ID

5777

NCBI登录号

NP_002822

UniProt

P29350

途径

JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling