Peroxiredoxin 2 抗体 (C-Term)
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- 抗原 See all Peroxiredoxin 2 (PRDX2) 抗体
- Peroxiredoxin 2 (PRDX2)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Peroxiredoxin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 序列
- C-NVDDSKEYFS KHN
- 特异性
- This antibody is expected to recognise isoforms a and b of Peroxiredoxin 2 only.
- 交叉反应 (详细)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse. - 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_005800.3, NP_859427.1.
- Top Product
- Discover our top product PRDX2 Primary Antibody
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- 应用备注
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ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % Sodium Azide, pH ~7.3 with 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Peroxiredoxin 2 (PRDX2)
- 别名
- Peroxiredoxin-2 / PRDX2 (PRDX2 产品)
- 背景
- The Peroxiredoxin (Prdx, Prx, or TrxPx) family of enzymes is a recently identified family of peroxidases found in free living organisms. The six known isoforms (Prx1 to 6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.Synonyms: NKEF-B, NKEFB, Natural killer cell-enhancing factor B, PRDX-2, PRP, Prx-2, Prx2, TDPX1, TSA, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1
- 基因ID
- 7001, 9606
- UniProt
- P32119
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