PAI1 抗体 (Internal Region)
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- 抗原 See all PAI1 (SERPINE1) 抗体
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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抗原表位
- Internal Region
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适用
- 人, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This PAI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- C-GFKIDDKGMA PALRH
- 交叉反应 (详细)
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Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human. - 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- 免疫原
- Synthetic peptide (C-GFKIDDKGMAPALRH) from the internal region of SERPINE1 (NP_000593.1, NP_001158885.1). Genename: SERPINE1
- Top Product
- Discover our top product SERPINE1 Primary Antibody
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- 应用备注
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Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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A unique microRNA signature associated with plaque instability in humans." in: Stroke, Vol. 42, Issue 9, pp. 2556-63, (2011) (PubMed).
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A unique microRNA signature associated with plaque instability in humans." in: Stroke, Vol. 42, Issue 9, pp. 2556-63, (2011) (PubMed).
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- 抗原
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- 别名
- SERPINE1 / PAI1 (SERPINE1 产品)
- 别名
- PAI antibody, PAI-1 antibody, PAI1 antibody, PLANH1 antibody, SERPINE1 antibody, si:ch211-138a11.1 antibody, Planh1 antibody, PAI1A antibody, Pai1 antibody, Pai1aa antibody, Planh antibody, RATPAI1A antibody, serpin family E member 1 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 1 antibody, SERPINE1 antibody, serpine1.L antibody, serpine1 antibody, Serpine1 antibody
- 背景
- PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1
- 分子量
- 45.1 kDa (NP_000593.1)
- NCBI登录号
- NM_000602
- UniProt
- P05121
- 途径
- p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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