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FTCD 抗体 (N-Term)

FTCD 适用: 人, 小鼠, Pig WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374453
发货至: 中国
  • 抗原 See all FTCD 抗体
    FTCD (Formiminotransferase Cyclodeaminase (FTCD))
    抗原表位
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Pig
    宿主
    • 19
    • 11
    • 5
    山羊
    克隆类型
    • 18
    • 16
    多克隆
    标记
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTCD antibody is un-conjugated
    应用范围
    • 27
    • 15
    • 9
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    SQLVECVPNF SEGKNQ
    特异性
    This antibody recognizes 58K Golgi protein at N-term.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Pig.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from the N-Terminus of the protein sequence according to NP_006648.1, NP_996848.1. Genename: FTCD
    Top Product
    Discover our top product FTCD Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.03-0.5 μg/mL. Detects a 55-60 kDa band in Human Liver lysate (PredictedMolecular Weight: 58.0 kDa). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Liver shows distinct staining of membranes and cytoplasm ina selection of hepatocytes.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FTCD (Formiminotransferase Cyclodeaminase (FTCD))
    别名
    58K Golgi Protein (FTCD 产品)
    背景
    58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1
    基因ID
    10841, 9606
    UniProt
    O95954
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