FTCD 抗体 (N-Term)
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- 抗原 See all FTCD 抗体
- FTCD (Formiminotransferase Cyclodeaminase (FTCD))
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抗原表位
- N-Term
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适用
- 人, 小鼠, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This FTCD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- SQLVECVPNF SEGKNQ
- 特异性
- This antibody recognizes 58K Golgi protein at N-term.
- 交叉反应 (详细)
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Species reactivity (expected):Mouse and Pig.
Species reactivity (tested):Human. - 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from the N-Terminus of the protein sequence according to NP_006648.1, NP_996848.1. Genename: FTCD
- Top Product
- Discover our top product FTCD Primary Antibody
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- 应用备注
- Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.03-0.5 μg/mL. Detects a 55-60 kDa band in Human Liver lysate (PredictedMolecular Weight: 58.0 kDa). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Liver shows distinct staining of membranes and cytoplasm ina selection of hepatocytes.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FTCD (Formiminotransferase Cyclodeaminase (FTCD))
- 别名
- 58K Golgi Protein (FTCD 产品)
- 背景
- 58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1
- 基因ID
- 10841, 9606
- UniProt
- O95954
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