BIM 抗体 (C-Term)
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- 抗原 See all BIM (BCL2L11) 抗体
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This BIM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- C-FNAYYARRLE K
- 特异性
- This antibody is expected to recognise 3 reported isoforms: BimAD, BimACD and BimABCD.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- 免疫原
- Peptide from the C Terminus of the protein sequence according to NP_619528, NP_996886, NP_619529.
- Top Product
- Discover our top product BCL2L11 Primary Antibody
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anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 2-120) antibody
BCL2L11 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer87) antibodyBCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibodyBCL2L11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160) antibodyBCL2L11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22105 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Middle Region) antibodyBCL2L11 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 51-150) antibodyBCL2L11 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer69) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody (Alkaline Phosphatase (AP))BCL2L11 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody (Biotin)BCL2L11 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
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- 应用备注
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Peptide ELISA: 1/16,000. Western Blot: 0.5-2 μg/mL. Detects a band of Approx 23 kDa in K562 lysates (PredictedMolecular Weight: 19.9, 12 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Abstract
- BCL2L11 产品
- 背景
- Bim, Bcl-2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in an inactive conformation through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibitory binding to anti-apoptotic Bcl-2 family members and subsequent iniation of apoptosis.Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS
- 基因ID
- 10018, 9606
- UniProt
- O43521
- 途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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