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TCP1 alpha/CCTA 抗体 (C-Term)

TCP1 适用: 人 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374406
发货至: 中国
  • 抗原 See all TCP1 alpha/CCTA (TCP1) 抗体
    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
    抗原表位
    • 40
    • 18
    • 18
    • 15
    • 15
    • 15
    • 15
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 170
    • 119
    • 77
    • 22
    • 21
    • 20
    • 19
    • 18
    • 17
    • 15
    • 13
    • 11
    • 10
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 151
    • 27
    • 18
    • 1
    • 1
    山羊
    克隆类型
    • 144
    • 54
    多克隆
    标记
    • 65
    • 14
    • 12
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TCP1 alpha/CCTA antibody is un-conjugated
    应用范围
    • 126
    • 53
    • 52
    • 45
    • 44
    • 40
    • 40
    • 27
    • 24
    • 21
    • 13
    • 11
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-SYEDAVHSGA LND
    特异性
    This antibody detects CCT1 / TCP1 at C-term. It is expected to recognise both reported isoforms.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from C Terminus of the protein sequence according to NP_110379.2, NP_001008897.1. Genename: TCP1
    Top Product
    Discover our top product TCP1 Primary Antibody
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 60 kDa band observed in Hela, Human Lung and HumanTestis lysates (predicted MW of 60 kDa according to NP_110379.2). Immunohistochemistry: 1-2 μg/mL. In paraffin embedded Human Testis shows onlycytoplasmic staining in some germ cells, and both cytoplasmic and nuclear staining inother germ cells with unstained nucleoli.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • 抗原
    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
    别名
    CCT1 / TCP1 (TCP1 产品)
    背景
    TCP1 alpha is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP 70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco subunit binding protein, and the archaebacterial protein TF55. The TCP1 sequence shows nearly 40 % identity to TF55, but only minimal similarity to HSP60 and GroEL.Synonyms: CCT alpha, CCTA, Chaperonin containing T complex polypeptide 1 subunit 1, T-complex protein 1 subunit alpha, TCP-1-alpha, TCP1 alpha
    基因ID
    6950
    NCBI登录号
    NP_110379
    UniProt
    P17987
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