IPO7 抗体 (C-Term)
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- 抗原 See all IPO7 抗体
- IPO7 (Importin 7 (IPO7))
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抗原表位
- C-Term
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适用
- 人, 小鼠, Cow, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This IPO7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- C-SSFNFGGPAP GMN
- 特异性
- This antibody detects RanBP7/Importin-7 at C-term.
- 交叉反应 （详细）
- Species reactivity (expected):Mouse, Rat, Dog, CowSpecies reactivity (tested):Human.
- 纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- 免疫原
- Synthetic peptide from C-terminus of Human IPO7 (NP_006382.1). Genename: IPO7
- Top Product
- Discover our top product IPO7 Primary Antibody
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anti-Importin 7 (IPO7) (AA 950-1038) antibody
IPO7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Importin 7 (IPO7) (C-Term) antibodyKO Validated IPO7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Importin 7 (IPO7) antibodyIPO7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 7 (IPO7) (AA 142-169), (N-Term) antibodyIPO7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26876 unconjugated
anti-Importin 7 (IPO7) (AA 1-50) antibodyIPO7 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: Limit dilution: 1/32000. Western blot: 0.1-1 μg/mL. Approx 120 kDa band observed in Human Brain lysates(predicted MW of 110 kDa according to NP_006382.1). Please note that an approx 30 kDaband of unknown identity is also consistently observed. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH 7.3 containing of 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- IPO7 (Importin 7 (IPO7))
- 别名
- RanBP7 / Importin-7 (IPO7 产品)
- 背景
- The Importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran binding site of importin beta. Similar to importin beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta like transport receptors, namely importin beta itself, transportin, RanBP5 and Importin 7, directly bind and import ribosomal proteins.Synonyms: IMP7, IPO7, Ran-binding protein 7
- 基因ID
- 10527
- NCBI登录号
- NP_006382
- UniProt
- O95373
- 途径
- Protein targeting to Nucleus
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