Peptide ELISA: 1/32000. Western blot: 1 - 3 μg/mL. Approx 35 kDa band observed in Human Brain and A431 lysates(calculated MW of 32.5 kDa according to NP_036418.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
0.5 mg/mL
缓冲液
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes mainly by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also be involved in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. May also interact with one or more as yet undefined members of the TLE (transducin like enhancer of split) family of transcriptional repressors.Synonyms: KIAA0026, MORF-related gene X protein, MORF4L2, MRGX, MSL3-2 protein, Mortality factor 4-like protein 2, Transcription factor-like protein MRGX