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SYT1 抗体 (pThr202)

SYT1 适用: 人, 大鼠, 小鼠, Cow, 小鸡, 犬, 斑马鱼, Non-Human Primate WB, IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372724
发货至: 中国
  • 抗原 See all SYT1 抗体
    SYT1 (Synaptotagmin I (SYT1))
    抗原表位
    • 15
    • 13
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr202
    适用
    • 82
    • 67
    • 47
    • 10
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 小鸡, 犬, 斑马鱼, Non-Human Primate
    宿主
    • 92
    • 12
    • 6
    • 1
    • 1
    • 1
    克隆类型
    • 101
    • 12
    多克隆
    标记
    • 63
    • 9
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    应用范围
    • 68
    • 44
    • 39
    • 16
    • 13
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)
    特异性
    This antibody recognizes the ~60k-62k synaptotagmin protein phosphorylated at Thr202 in Western Blots of Rat brain lysate. The immunolabeling is completely eliminated by lambda-phosphatase treatment.
    交叉反应 (详细)
    Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse, non-Human Primate and Zebrafish.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr202 of Synaptotagmin.
    亚型
    IgG
    Top Product
    Discover our top product SYT1 Primary Antibody
  • 应用备注
    Dot blot: 1/1,000. Western blot: 1/1,000. Immunohistochemistry: 1/400.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    SYT1 (Synaptotagmin I (SYT1))
    别名
    Synaptotagmin-1 (SYT1 产品)
    背景
    Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001, Wang et al., 2003). Moreover, recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin's ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999, Lee et al., 2004).Synonyms: SYT1, SYT2, SYT3, SYT4, SYT5
    基因ID
    6857
    NCBI登录号
    NP_001129277
    UniProt
    P21579
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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