SYN1 抗体 (pSer549)
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- 抗原 See all SYN1 抗体
- SYN1 (Synapsin I (SYN1))
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抗原表位
- pSer549
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Non-Human Primate
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)
- 特异性
- This antibody recognizes the ~78k Synapsin I doublet protein phosphorylated at Ser549. Immunolabeling of the synapsin I band is blocked by lambda-phosphatase treatment.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Canine, Mouse and non-Human Primates.
Species reactivity (tested):Rat. - 纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of Synapsin I.
- 亚型
- IgG
- Top Product
- Discover our top product SYN1 Primary Antibody
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anti-Synapsin I (SYN1) (AA 362-511) antibody
SYN1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7H10G6 unconjugated
anti-Synapsin I (SYN1) (AA 113-420) antibodySYN1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (AA 362-450) antibodySYN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) antibodySYN1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) antibodySYN1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer62), (pSer67) antibodySYN1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer549) antibodySYN1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/1,000. Immunohistochemistry: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- SYN1 (Synapsin I (SYN1))
- 别名
- Synapsin-1 (SYN1 产品)
- 背景
- Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.Synonyms: Brain protein 4.1, SYN1, Synapsin I
- 基因ID
- 6853
- NCBI登录号
- NP_008881
- UniProt
- P17600
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