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SYN1 抗体 (pSer62, pSer67)

Name: SYN1 抗体 (pSer62, pSer67)
SKU: ABIN372719
Availability: OutOfStock

SYN1 适用: 小鼠, 大鼠, Cow WB, DB 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Synapsin I (SYN1) (pSer62), (pSer67) antibody (ABIN372719) (SYN1 抗体 (pSer62, pSer67))

1 image

(1 reference)

产品编号 ABIN372719

发货至: 中国

Datasheet as PDF

抗原 See all SYN1 抗体

SYN1 (Synapsin I (SYN1))
抗原表位
27

15

14

11

7

5

4

4

4

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer62, pSer67
适用
112

88

67

14

5

4

2

2

1

1
小鼠, 大鼠, Cow
宿主
120

7
兔
Compatible Secondaries
克隆类型
113

14
多克隆
标记
80

6

4

4

4

4

4

4

4

2

1

1

1

1

1

1

1

1

1

1

1
This SYN1 antibody is un-conjugated
应用范围
91

48

38

23

14

13

13

8

7

7

3

2

2

1

1
Western Blotting (WB), Dot Blot (DB)

特异性

This antibody recognizes the ~78k Synapsin I doublet phosphorylated at Ser62,67. Immunolabeling of the Synapsin I band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding dephospho-peptide.

交叉反应（详细）

Species reactivity (expected):Bovine (100 %) and Mouse (100 %).
Species reactivity (tested):Rat.

纯化方法

Sequential Chromatography on phospho- and dephosphopeptide affinity columns

免疫原

Phosphopeptide corresponding to amino acid residues surrounding the Phospho Serine 62,67 of Synapsin I.

亚型

IgG

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anti-Synapsin I (SYN1) (AA 113-420) antibody
SYN1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Synapsin I (SYN1) (AA 362-450) antibody
SYN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated

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anti-Synapsin I (SYN1) (pSer9) antibody
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anti-Synapsin I (SYN1) (pSer9) antibody
SYN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synapsin I (SYN1) antibody
SYN1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synapsin I (SYN1) (pSer62), (pSer67) antibody
SYN1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Synapsin I (SYN1) (pSer549) antibody
SYN1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES ( pH 7.5), 150 mM NaCl, None, 100 μg/mL BSA and 50 % Glycerol

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody undiluted (in aliquots) at-20 °C.
Tallent, Varghis, Skorobogatko, Hernandez-Cuebas, Whelan, Vocadlo, Vosseller: "In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 174-81, (2008) (PubMed).
抗原

SYN1 (Synapsin I (SYN1))

别名

Synapsin-1 (SYN1 产品)

背景

Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of Synapsin I that are phosphorylated by MAP kinase (Czernik et al., 1987, Jovanovic et al., 1996).Synonyms: Brain protein 4.1, SYN1, Synapsin I

基因ID

6853

NCBI登录号

NP_008881

UniProt

P17600