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RPS6KA3 抗体 (C-Term)
RPS6KA3
适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡
WB
宿主: 兔
Polyclonal
unconjugated
RPS6KA3抗体详情
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抗原
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RPS6KA3
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
抗原表位
All epitopes for RPS6KA3 抗体
C-Term
适用
All reactivities for RPS6KA3 抗体
人, 小鼠, 大鼠, Cow, 犬, 小鸡
宿主
All hosts for RPS6KA3 抗体
兔
克隆类型
All clonalities for RPS6KA3 抗体
多克隆
标记
All conjugates for RPS6KA3 抗体
This RPS6KA3 antibody is un-conjugated
应用范围
All applications for RPS6KA3 抗体
Western Blotting (WB)
特异性
This antibody recognizes the ~90k RSK2 protein.
交叉反应 (详细)
Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat. Species reactivity (tested):Human.
纯化方法
Affinity Chromatography.
免疫原
Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).
亚型
IgG
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Alternatives
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使用细节
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应用备注
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Store the antibody undiluted (in aliquots) at-20 °C.
RPS6KA3目标详情
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抗原
RPS6KA3
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
别名
RPS6KA3 / RSK2 (RPS6KA3 产品 )
背景
The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3
基因ID
6197
NCBI登录号
NP_004577
UniProt
P51812
途径
MAPK Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
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