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RPS6KA3 抗体 (C-Term)

RPS6KA3 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372713
发货至: 中国
  • 抗原 See all RPS6KA3 抗体
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    抗原表位
    • 24
    • 23
    • 18
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    C-Term
    适用
    • 172
    • 113
    • 64
    • 2
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    • 1
    • 1
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    • 1
    人, 小鼠, 大鼠, Cow, 犬, 小鸡
    宿主
    • 173
    • 17
    • 1
    克隆类型
    • 173
    • 18
    多克隆
    标记
    • 72
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    This RPS6KA3 antibody is un-conjugated
    应用范围
    • 96
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    • 53
    • 30
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    • 14
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    Western Blotting (WB)
    特异性
    This antibody recognizes the ~90k RSK2 protein.
    交叉反应 (详细)
    Species reactivity (expected):Bovine, Canine, Chicken, Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography.
    免疫原
    Peptide corresponding to amino acid residues from the C-terminal region of rat RSK2, conjugated to keyhole limpet hemocyanin (KLH).
    亚型
    IgG
    Top Product
    Discover our top product RPS6KA3 Primary Antibody
  • 应用备注
    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    别名
    RPS6KA3 / RSK2 (RPS6KA3 产品)
    背景
    The p90 Ribosomal S6 kinases (RSK1-4) are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3
    基因ID
    6197
    NCBI登录号
    NP_004577
    UniProt
    P51812
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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