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MAPK14 抗体 (pThr180, pTyr182)

Name: MAPK14 抗体 (pThr180, pTyr182)
SKU: ABIN372694
Availability: OutOfStock

MAPK14 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, 斑马鱼, Non-Human Primate WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (pThr180), (pTyr182) antibody (ABIN372694) (MAPK14 抗体 (pThr180, pTyr182))

1 image

(1 reference)

产品编号 ABIN372694

发货至: 中国

Datasheet as PDF

抗原 See all MAPK14 抗体

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
抗原表位
40

33

18

16

16

7

7

6

5

5

5

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr180, pTyr182
适用
229

148

136

27

24

22

16

13

12

11

9

7

6

3

3

3

2

1

1

1

1
人, 小鼠, 大鼠, 犬, 小鸡, Cow, 斑马鱼, Non-Human Primate
宿主
200

31

2

1
兔
Compatible Secondaries
克隆类型
185

51
多克隆
标记
136

10

10

7

7

5

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1
This MAPK14 antibody is un-conjugated
应用范围
184

92

70

50

43

38

37

29

28

22

10

9

5

5

4

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

This antibody recognizes the ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182. Immunolabeling is blocked by preadsorption of the antibody with the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.

交叉反应（详细）

Species reactivity (expected):Bovine, Canine, Chicken, Mouse, Zebrafish and non-Human Primates.
Species reactivity (tested):Human.

纯化方法

Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

免疫原

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr180 and phospho-Tyr182 of rat p38 MAPK.

亚型

IgG

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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8G4D11 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 141-240) antibody
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anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 19-279) antibody
MAPK14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 260-360) antibody
MAPK14 适用: 人 WB, ELISA, IP, IHC (p), PLA 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 10B11C8 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 295-324), (C-Term) antibody
MAPK14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB2723 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody
MAPK14 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (C-Term) antibody
MAPK14 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

应用备注

Western blot: 1/1000. Immunohistochemistry: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody undiluted (in aliquots) at-20 °C.
Chaudhuri, Ghate, Singh, Mandal: "Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal-regulated kinase 1/2 activation." in: Pharmacognosy magazine, Vol. 11, Issue 42, pp. 269-76, (2015) (PubMed).
抗原

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

别名

MAP Kinase p38 alpha / MAPK14 (MAPK14 产品)

背景

The three Mitogen-Activated Protein Kinases (MAPKs) are evolutionarily conserved protein kinases that control a vast array of cellular processes. p38 MAPK is one of these kinases and it is activated by both inflammatory cytokines and by stress (Johnson and Lapadat, 2002, Shi and Gaestel, 2002). The p38 MAPK is thought to be particularly important in diseases like asthma and autoimmunity but it also plays important roles in the stress response of the nervous system (Philip and Armstead, 2003, Ying et al., 2002). Like the other MAPKs, p38 is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182 (Lin et al., 1995).Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha

基因ID

1432

NCBI登录号

NP_001306

UniProt

Q16539

途径

MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins