OLIG2 抗体
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- 抗原 See all OLIG2 抗体
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OLIG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognizes the ~32 kDa Olig2 protein in Western blots.
- 交叉反应 (详细)
- Species reactivity (tested):Human, Mouse and Rat.
- 纯化方法
- Protein A Chromatography.
- 免疫原
- Recombinant Mouse Olig2.
- 亚型
- IgG
- Top Product
- Discover our top product OLIG2 Primary Antibody
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- 应用备注
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Western blot: 1/3000. Immunohistochemistry: 1/1000. Immunocytochemistry: 1/1000. Immunoprecipitation: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 mM Glycine, 200 mM Tris, pH 8.0 without preservatives.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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Histone deacetylase 3 is necessary for proper brain development." in: The Journal of biological chemistry, Vol. 289, Issue 50, pp. 34569-82, (2014) (PubMed).
: "Loss of caveolin-1 from bronchial epithelial cells and monocytes in human subjects with asthma." in: Allergy, Vol. 67, Issue 12, pp. 1601-4, (2012) (PubMed).
: "Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33138-46, (2008) (PubMed).
: "Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons." in: The Journal of physiology, Vol. 581, Issue Pt 3, pp. 941-60, (2007) (PubMed).
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Histone deacetylase 3 is necessary for proper brain development." in: The Journal of biological chemistry, Vol. 289, Issue 50, pp. 34569-82, (2014) (PubMed).
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- 抗原
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
- 别名
- OLIG2 (OLIG2 产品)
- 别名
- olig3.2 antibody, MGC89336 antibody, OLIG2 antibody, BHLHB1 antibody, OLIGO2 antibody, PRKCBP2 antibody, RACK17 antibody, bHLHe19 antibody, wu:fc64g09 antibody, AI604895 antibody, Bhlhb1 antibody, Olg-2 antibody, Oligo2 antibody, RK17 antibody, oligodendrocyte transcription factor 4 antibody, oligodendrocyte transcription factor 2 antibody, oligodendrocyte lineage transcription factor 2 antibody, olig4 antibody, OLIG2 antibody, Olig2 antibody, olig2 antibody
- 背景
- Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).Synonyms: BHLHB1, Class B basic helix-loop-helix protein 1, OLIG2, Oligo2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17, bHLHB1
- 基因ID
- 10215
- NCBI登录号
- NP_005797
- UniProt
- Q13516
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