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STXBP1 抗体 (pSer515)

STXBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 非洲爪蟾 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372671
发货至: 中国
  • 抗原 See all STXBP1 抗体
    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
    抗原表位
    • 15
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer515
    适用
    • 49
    • 41
    • 32
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 小鸡, 非洲爪蟾
    宿主
    • 58
    • 6
    • 2
    克隆类型
    • 60
    • 6
    多克隆
    标记
    • 39
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STXBP1 antibody is un-conjugated
    应用范围
    • 50
    • 27
    • 13
    • 13
    • 12
    • 9
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser515 of Munc-18.
    亚型
    IgG
    Top Product
    Discover our top product STXBP1 Primary Antibody
  • 应用备注
    Western blot: 1/1000. Immunohistochemistry: 1/400. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20°C.
    有效期
    12 months
  • 抗原
    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
    别名
    STXBP1 / UNC18A (STXBP1 产品)
    背景
    Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).
    Alternate names: N-Sec1, Syntaxin-binding protein 1, Unc-18 homolog, Unc-18-1, Unc-18A
    基因ID
    25558
    NCBI登录号
    NP_037170
    UniProt
    P61765
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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