Connexin 43/GJA1 抗体 (C-Term)
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- 抗原 See all Connexin 43/GJA1 (GJA1) 抗体
- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 犬, 小鸡, 斑马鱼, 绵羊, Finch, Non-Human Primate, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Connexin 43/GJA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~43k Connexin-43 protein.
- 交叉反应 (详细)
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Species reactivity (expected):Human, Chicken, Canine (Dog), Finch, Mouse, Sheep, Xenopus, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat. - 纯化方法
- Affinity Chromatography.
- 免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat Connexin-43.
- 亚型
- IgG
- Top Product
- Discover our top product GJA1 Primary Antibody
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- 应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
- 别名
- GJA1 / Cx43 (GJA1 产品)
- 别名
- AVSD3 antibody, CX43 antibody, DFNB38 antibody, GJAL antibody, HLHS1 antibody, HSS antibody, ODDD antibody, Cx43 antibody, AU042049 antibody, AW546267 antibody, Cnx43 antibody, Cx43alpha1 antibody, Gja-1 antibody, Npm1 antibody, connexin43 antibody, cx43a1 antibody, gja1 antibody, zfCx43.3 antibody, connexin 43 antibody, gja1-A antibody, cx43 antibody, gjal antibody, oddd antibody, dfnb38 antibody, gap junction protein alpha 1 antibody, gap junction protein, alpha 1 antibody, connexin 43 antibody, gap junction protein alpha 1 L homeolog antibody, CONNEXIN 43 protein antibody, GJA1 antibody, Gja1 antibody, cx43 antibody, gja1.L antibody, gja1 antibody, CONNEXIN 43 antibody
- 背景
- Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
- 基因ID
- 2697
- NCBI登录号
- NP_000156
- UniProt
- P17302
- 途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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