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CDK1 抗体 (pTyr15)
CDK1
适用: 人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
CDK1抗体详情
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抗原
See all CDK1 抗体
CDK1
(Cyclin-Dependent Kinase 1 (CDK1))
抗原表位
All epitopes for CDK1 抗体
pTyr15
适用
All reactivities for CDK1 抗体
人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼
宿主
All hosts for CDK1 抗体
兔
克隆类型
All clonalities for CDK1 抗体
多克隆
标记
All conjugates for CDK1 抗体
This CDK1 antibody is un-conjugated
应用范围
All applications for CDK1 抗体
Western Blotting (WB)
特异性
Specific for the ~38k CDC2 protein phosphorylated at Tyr15. Immunolabeling is blocked by the lambda-phosphatase treatment.
交叉反应 (详细)
Species reactivity (expected):Mouse, Rat and Zebrafish. Species reactivity (tested):Human and Xenopus.
纯化方法
Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
免疫原
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Tyr15 of rat CDC2.
亚型
IgG
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Alternatives
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使用细节
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应用备注
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Store the antibody undiluted (in aliquots) at-20 °C.
CDK1目标详情
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抗原
CDK1
(Cyclin-Dependent Kinase 1 (CDK1))
别名
CDK1 (CDK1 产品 )
背景
Cdc2 is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle (Maller, 1991). The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2 (Nakamizo et al., 2002). cdc2 expression in brain has been linked to both neurogenesis and apoptosis (Konishi and Bonni, 2003, Dranovsky et al., 2001, Okano et al., 1996).Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase
基因ID
983
NCBI登录号
NP_001777
UniProt
P06493
途径
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Mitotic G1-G1/S Phases , DNA Replication , M Phase , Toll-Like Receptors Cascades , Synthesis of DNA
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