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THRA 抗体 (N-Term)
THRA
适用: 人, 小鼠, 大鼠, 犬
WB
宿主: 小鼠
Monoclonal
2103
unconjugated
THRA抗体详情
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抗原
See all THRA 抗体
THRA
(Thyroid Hormone Receptor, alpha (THRA))
抗原表位
All epitopes for THRA 抗体
N-Term
适用
All reactivities for THRA 抗体
人, 小鼠, 大鼠, 犬
宿主
All hosts for THRA 抗体
小鼠
克隆类型
All clonalities for THRA 抗体
单克隆
标记
All conjugates for THRA 抗体
This THRA antibody is un-conjugated
应用范围
All applications for THRA 抗体
Western Blotting (WB)
特异性
AM08268PU-N is specific for the ~50k THR alpha-1 and the ~58k THR alpha-2 proteins.
交叉反应 (详细)
Species reactivity (expected):Canine (Dog), Mouse and Rat. Species reactivity (tested):Human.
产品特性
Synonyms: Thyroid hormone receptor alpha, THRA1, THRA2, C-erbA-alpha, c-erbA-1, EAR-7, EAR7,NR1A1, Nuclear receptor subfamily 1 group A member 1
纯化方法
Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
免疫原
Peptide corresponding to amino acid residues from the N-terminal region of human thyroidhormone receptor, alpha1/alpha2-isotype.
克隆位点
2103
亚型
IgG1
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Alternatives
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使用细节
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应用备注
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
储存条件
-20 °C
储存方法
Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
THRA目标详情
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抗原
THRA
(Thyroid Hormone Receptor, alpha (THRA))
别名
THRA / ERBA1 (THRA 产品 )
别名
AR7 antibody, CHNG6 antibody, EAR7 antibody, ERB-T-1 antibody, ERBA antibody, ERBA1 antibody, NR1A1 antibody, THRA1 antibody, THRA2 antibody, c-ERBA-1 antibody, C-ERBA-ALPHA antibody, TRalpha antibody, c-erba antibody, erba antibody, nr1a1-A antibody, thra-A antibody, thra1 antibody, TR[a]1 antibody, nr1a1 antibody, thra antibody, thral antibody, tra antibody, tra1 antibody, wu:fb59g07 antibody, Thra1 antibody, 6430529J03Rik antibody, AW259572 antibody, Erba antibody, Nr1a1 antibody, Rvr antibody, T3R[a] antibody, T3Ralpha antibody, Thra2 antibody, C-ERBA ALPHA1 antibody, Thra antibody, fTHRalphaA antibody, nr1a1-a antibody, thyroid hormone receptor, alpha antibody, thyroid hormone receptor, alpha L homeolog antibody, thyroid hormone receptor alpha a antibody, thyroid hormone receptor alpha antibody, thyroid hormone receptor alpha-A antibody, THRA antibody, thra.L antibody, thraa antibody, Thra antibody, tr-alpha antibody, LOC109641414 antibody
背景
Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TR-alpha1, TR-alpha2, TR-beta1 and TR-beta2. TR-alpha1, TR-beta1 and TR-beta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).Synonyms: C-erbA-alpha, EAR-7, EAR7, NR1A1, Nuclear receptor subfamily 1 group A member 1, THRA1, THRA2, Thyroid hormone receptor alpha, c-erbA-1
基因ID
7067
UniProt
P10827
途径
Nuclear Receptor Transcription Pathway , Steroid Hormone Mediated Signaling Pathway , Sensory Perception of Sound , Cellular Response to Molecule of Bacterial Origin , Regulation of Lipid Metabolism by PPARalpha , Regulation of Muscle Cell Differentiation , Maintenance of Protein Location , Skeletal Muscle Fiber Development
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