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APEX1 抗体

APEX1 适用: 人, 小鼠, 大鼠, 兔 WB, IHC, IF, ChIP, ICC, IP, Neut 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN363379
发货至: 中国
  • 抗原 See all APEX1 抗体
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    适用
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    人, 小鼠, 大鼠, 兔
    宿主
    • 73
    • 18
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    克隆类型
    • 76
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    多克隆
    标记
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    This APEX1 antibody is un-conjugated
    应用范围
    • 79
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC), Immunoprecipitation (IP), Neutralization (Neut)
    特异性
    Reacts with human ~37 kDa APE-1 protein
    交叉反应
    小鼠, 兔, 大鼠
    交叉反应 (详细)
    Cross reacts with proteins from mouse, rat and rabbit.
    纯化方法
    Antigen affinity purified
    免疫原
    Affinity purified human Apurinic/Apyrimidinic Endonuclease (APE/ref-1) fusion protein
    Top Product
    Discover our top product APEX1 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IHC: 1/1 000 - WB : 1/1 000 - B/N: 50-200 Molar excess - ChIP: 1/10-1/500 - ICC/IF: 1/50-1/200 - IP: 7 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Tris-glycine, NaCl 150 mM buffer, Sodium azide 0.05 %
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
  • 抗原
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    别名
    DNA-(Apurinic Or Apyrimidinic Site) Lyase (APE-1) (APEX1 产品)
    别名
    apex1 antibody, MGC76280 antibody, MGC79645 antibody, MGC78928 antibody, APE antibody, APE1 antibody, APEN antibody, APEX antibody, APX antibody, HAP1 antibody, REF1 antibody, Apex antibody, REF-1 antibody, BAP1 antibody, apex1a antibody, hm:zehn1532 antibody, wu:fc13d11 antibody, zgc:66204 antibody, Ref-1 antibody, apurinic/apyrimidinic endodeoxyribonuclease 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antibody, DNA-(apurinic or apyrimidinic site) lyase antibody, apurinic/apyrimidinic endonuclease 1 antibody, APEX1 antibody, apex1 antibody, apex1.L antibody, CNG03640 antibody, CNH01280 antibody, nth antibody, Spirs_4119 antibody, Palpr_0103 antibody, Apex1 antibody
    背景
    Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.
    基因ID
    328
    途径
    DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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