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VASP 抗体 (AA 155-159)

VASP 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362855
发货至: 中国
  • 抗原 See all VASP 抗体
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    抗原表位
    • 17
    • 16
    • 15
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 155-159
    适用
    • 123
    • 58
    • 54
    • 11
    • 9
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 105
    • 17
    • 2
    克隆类型
    • 101
    • 23
    多克隆
    标记
    • 79
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VASP antibody is un-conjugated
    应用范围
    • 97
    • 48
    • 46
    • 27
    • 22
    • 14
    • 14
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of total VASP protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    免疫原
    Peptide sequence around AA 155-159 (R-V-S-N-A) derived from Human VASP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
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    Discover our top product VASP Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    别名
    VASP (VASP 产品)
    背景
    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
    分子量
    50 kDa
    NCBI登录号
    NP_003361
    UniProt
    P50552
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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