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- 抗原 See all ICAM1 抗体
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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抗原表位
- AA 510-514
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ICAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of total ICAM-1 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- 免疫原
- Peptide sequence around AA 510-514 (K-K-Y-R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- 应用备注
- Western blotting: 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK." in: Free radical biology & medicine, Vol. 50, Issue 9, pp. 1094-106, (2011) (PubMed).
: "A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons." in: PLoS ONE, Vol. 4, Issue 12, pp. e8289, (2009) (PubMed).
: "Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes." in: Glia, Vol. 58, Issue 3, pp. 344-66, (2009) (PubMed).
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Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK." in: Free radical biology & medicine, Vol. 50, Issue 9, pp. 1094-106, (2011) (PubMed).
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- 抗原
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 别名
- ICAM-1 (ICAM1 产品)
- 别名
- BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
- 物质类
- Viral Protein
- 背景
- ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
- 分子量
- 92 kDa
- NCBI登录号
- NP_000192
- UniProt
- P05362
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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