The antibody detects endogenous level of total Ezrin protein.
纯化方法
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity Ezrin (Ab-353) antibody detects endogenous levels of total Ezrin protein.
免疫原
Peptide sequence around AA 351-355 (Q-D-Y-E-E) derived from Human EZRIN. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.