-
- 抗原 See all SMAD2 抗体
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
-
抗原表位
- pThr220
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SMAD2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of Smad2 only when phosphorylated at threonine 220.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pThr220 (P-E-T (p) -P-P) derived from Human Smad2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product SMAD2 Primary Antibody
-
-
- 应用备注
- Western blotting: 1:500-1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice." in: PLoS ONE, Vol. 8, Issue 3, pp. e59002, (2013) (PubMed).
: "
-
Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice." in: PLoS ONE, Vol. 8, Issue 3, pp. e59002, (2013) (PubMed).
-
- 抗原
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- 别名
- Smad2 (SMAD2 产品)
- 别名
- JV18 antibody, JV18-1 antibody, MADH2 antibody, MADR2 antibody, hMAD-2 antibody, hSMAD2 antibody, jv18 antibody, Xmad2 antibody, madh2 antibody, madr2 antibody, XSmad2 antibody, hmad-2 antibody, hsmad2 antibody, jv18-1 antibody, smad-2 antibody, fj43c06 antibody, wu:fj43c06 antibody, 7120426M23Rik antibody, Madh2 antibody, Madr2 antibody, Smad-2 antibody, mMad2 antibody, MAD homolog 2 antibody, Mothers against DPP homolog 2 antibody, SMAD 2 antibody, Smad2 antibody, SMAD family member 2 antibody, SMAD family member 2-Z antibody, SMAD family member 2 S homeolog antibody, SMAD2 antibody, SMAD2Z antibody, smad2 antibody, smad2.S antibody, Smad2 antibody
- 背景
- Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
- 分子量
- 60 kDa
- UniProt
- Q15796
- 途径
- Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
-