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- 抗原 See all MEF2A 抗体
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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抗原表位
- pThr312
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEF2A antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 特异性
- The antibody detects endogenous level of MEF2A only when phosphorylated at threonine 312.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pThr312 (L-A-T (p) -P-V) derived from Human MEF2A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product MEF2A Primary Antibody
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- 应用备注
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7623-30, (2007) (PubMed).
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Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus development." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7623-30, (2007) (PubMed).
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- 抗原
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- 别名
- MEF2A (MEF2A 产品)
- 别名
- ADCAD1 antibody, RSRFC4 antibody, RSRFC9 antibody, mef2 antibody, A430079H05Rik antibody, mef2a antibody, wu:fd19d02 antibody, adcad1 antibody, rsrfc4 antibody, rsrfc9 antibody, sl2 antibody, MEF2A antibody, xmef2a antibody, myocyte enhancer factor 2A antibody, myocyte enhancer factor 2aa antibody, myocyte enhancer factor 2a antibody, myocyte-specific enhancer factor 2A antibody, myocyte-specific enhancer factor 2a, putative antibody, myocyte enhancer factor 2A L homeolog antibody, MEF2A antibody, Mef2a antibody, mef2aa antibody, EDI_092490 antibody, EDI_038250 antibody, Smp_161530 antibody, mef2a.L antibody, mef2a antibody, LOC539054 antibody
- 背景
- The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain
- 分子量
- 54 kDa
- NCBI登录号
- NP_001124
- UniProt
- Q02078
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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