Calnexin 抗体 (C-Term)
(6 references)-
- 抗原 See all Calnexin (CANX) 抗体
- Calnexin (CANX)
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抗原表位
- C-Term
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适用
- 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Calnexin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects the C-terminal domain of Calnexin ~90 kDa. Weak detection in Chicken, Drosophila, and Xenopus tissues
- 交叉反应
- 小鸡, Cow, 犬, Drosophila melanogaster, 豚鼠, Hamster, 人, 猴, 小鼠, Pig, Quail, 兔, 大鼠, 绵羊, 非洲爪蟾
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Dog calnexin C-terminal synthetic peptide conjugated to KLH. Identical to human, mouse and rat calnexin sequences over these residues.
- Top Product
- Discover our top product CANX Primary Antibody
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anti-Calnexin (CANX) (C-Term) antibody
CANX 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, Pig, 猴, Hamster, 绵羊, 小鸡, Avian, 马, 山羊, Cat, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Calnexin (CANX) (Internal Region) antibodyCANX 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calnexin (CANX) (AA 263-482) antibodyCANX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calnexin (CANX) (AA 504-592) antibodyCANX 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Calnexin (CANX) (AA 1-300), (N-Term) antibodyCANX 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CANX-1541 unconjugated
anti-Calnexin (CANX) (AA 239-461) antibodyCANX 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calnexin (CANX) (AA 239-461) antibodyCANX 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Calnexin (CANX) antibodyCANX 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calnexin (CANX) (AA 1-300), (N-Term) antibodyCANX 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CANX-1543 unconjugated
anti-Calnexin (CANX) (C-Term) antibodyCANX 适用: 犬 WB, IHC, IF, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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- WB (1:1000)
- IHC (1:100)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:1000 dilution of ABIN361826 was sufficient for detection of Calnexin in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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: "Characterization of the African Swine Fever Virus Decapping Enzyme during Infection." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).
: "Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. ..." in: Autophagy, Vol. 12, Issue 11, pp. 2213-2229, (2017) (PubMed).
: "Heterozygous ABCB4 mutations in children with cholestatic liver disease." in: Liver international : official journal of the International Association for the Study of the Liver, (2015) (PubMed).
: "Functional analysis of ABCB4 mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity." in: Gut, Vol. 64, Issue 1, pp. 147-55, (2014) (PubMed).
: "Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues." in: Cell and tissue research, Vol. 358, Issue 2, pp. 331-42, (2014) (PubMed).
: "The composition of West Nile virus lipid envelope unveils a role of sphingolipid metabolism in flavivirus biogenesis." in: Journal of virology, Vol. 88, Issue 20, pp. 12041-54, (2014) (PubMed).
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: "Characterization of the African Swine Fever Virus Decapping Enzyme during Infection." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).
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- 抗原
- Calnexin (CANX)
- 别名
- Calnexin (CANX 产品)
- 别名
- CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
- 背景
- Calnexin, an abundant ~90 kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50 kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their C-terminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multi-subunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their mono-glycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatibility complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7).
- 基因ID
- 403908
- NCBI登录号
- NP_001003232
- UniProt
- P24643
- 途径
- MAPK Pathway, Thyroid Hormone Synthesis
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