SOD2 抗体
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- 抗原 See all SOD2 抗体
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Detects ~25 kDa.
- 交叉反应
- 小鸡, Cow, 犬, Drosophila melanogaster, 豚鼠, Hamster, 人, Invertebrate, 猴, 小鼠, Pig, 兔, 大鼠, Sea Squirt, 绵羊, Squirrel, 非洲爪蟾
- 纯化方法
- Protein A Purified
- 免疫原
- Recombinant Rat Mn SOD Protein
- Top Product
- Discover our top product SOD2 Primary Antibody
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- 应用备注
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- WB (1:5000)
- IHC (1:100)
- ICC/IF (1:120)
- optimal dilutions for assays should be determined by the user.
- 说明
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0.5 μg/ml of ABIN361655 was sufficient for detection of Mn SOD in 20 μg of rat brain tissue extract by colorimetric immunoblot analysis using Goat anti-rabbit IgG:AP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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Expression of NF-?B and downstream antioxidant genes in skeletal muscle of hibernating ground squirrels, Spermophilus tridecemlineatus." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 166-74, (2012) (PubMed).
: "Cytosolic subunits of ATP synthase are localized to the cortical endoplasmic reticulum-rich domain of the ascidian egg myoplasm." in: Development, growth & differentiation, Vol. 54, Issue 8, pp. 753-66, (2012) (PubMed).
: "Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat." in: Journal of biomedical science, Vol. 16, pp. 19, (2009) (PubMed).
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Expression of NF-?B and downstream antioxidant genes in skeletal muscle of hibernating ground squirrels, Spermophilus tridecemlineatus." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 166-74, (2012) (PubMed).
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- 抗原
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- 别名
- SOD2 (SOD2 产品)
- 别名
- LOC100101896 antibody, MNSOD antibody, GB14346 antibody, sod2 antibody, MGC88869 antibody, Sod2 antibody, CG8905 antibody, Dmel\\CG8905 antibody, Mito SOD antibody, Mn SOD antibody, Mn-SOD antibody, Mn-SOD2 antibody, MnSOD antibody, MnSODII antibody, Mn[2+]SOD antibody, SOD antibody, SOD-2 antibody, SOD2 antibody, Sod-2 antibody, dSOD2 antibody, mitSOD2 antibody, mnSOD antibody, IPOB antibody, MVCD6 antibody, cb463 antibody, wu:fj33b01 antibody, zgc:73051 antibody, MnSOD antibody, manganese superoxide dismutase antibody, superoxide dismutase 2, mitochondrial antibody, superoxide dismutase 2 antibody, Mn superoxide dismutase antibody, Superoxide dismutase 2 (Mn) antibody, superoxide dismutase 2 L homeolog antibody, BDBG_07234 antibody, LOC100101896 antibody, MNSOD antibody, Sod2 antibody, sod2 antibody, LbMnSOD4 antibody, SOD2 antibody, LOC100282741 antibody, SOD-2 antibody, sod2.L antibody
- 背景
- Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2ˉ to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (7). SOD3 can also be distinguished by its heparin-binding capacity (1).
- 基因ID
- 24787
- NCBI登录号
- NP_058747
- UniProt
- P07895
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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