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- 抗原 See all RPS6KA2 抗体
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPS6KA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~90k RSK2 protein.
- 交叉反应
- 人
- 预测反应
- bovine, canine, chicken, mouse, rat
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
- Top Product
- Discover our top product RPS6KA2 Primary Antibody
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- 应用备注
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).
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Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 41, Issue 12, pp. 2920-2931, (2017) (PubMed).
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- 抗原
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- 别名
- RPS6KA2 (RPS6KA2 产品)
- 别名
- HU-2 antibody, MAPKAPK1C antibody, RSK antibody, RSK3 antibody, S6K-alpha antibody, S6K-alpha2 antibody, p90-RSK3 antibody, pp90RSK3 antibody, 90kDa antibody, D17Wsu134e antibody, Rps6ka-rs1 antibody, Rsk3 antibody, p90rsk antibody, pp90rsk antibody, ribosomal protein S6 kinase A2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, Rps6ka2 antibody, RPS6KA2 antibody
- 背景
- The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). Anti-Ribosomal S6 Kinase Western blot of rat hippocampal lysate showing specific immunolabeling of the ~90k RSK2 protein.
- 分子量
- '90 kDa
- 基因ID
- 20112
- UniProt
- Q9WUT3
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
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