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- 抗原 See all YWHAB 抗体
- YWHAB (14-3-3 alpha + beta (YWHAB))
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抗原表位
- pSer58
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YWHAB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for the ~29k 14-3-3 protein phosphorylated at Ser58. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
- 交叉反应
- 人, 大鼠
- 预测反应
- bovine, canine, chicken, mouse, non-human primates, sheep, Xenopus, zebra fish
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58 conjugated to KLH
- Top Product
- Discover our top product YWHAB Primary Antibody
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anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibody
YWHAB 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibodyYWHAB 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 5B5G10 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (Center) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-246) antibodyYWHAB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 1-141) antibodyYWHAB 适用: 人, 斑马鱼 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 34-221) antibodyYWHAB 适用: 人, 斑马鱼 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 56-85), (N-Term) antibodyYWHAB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4062 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 217-246), (C-Term) antibodyYWHAB 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4064 unconjugated
anti-14-3-3 alpha + beta (YWHAB) (AA 51-150) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 alpha + beta (YWHAB) (C-Term) antibodyYWHAB 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended Dilution: WB: 1:1000 IHC: 1:500 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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- 抗原
- YWHAB (14-3-3 alpha + beta (YWHAB))
- 别名
- YWHAB (YWHAB 产品)
- 别名
- GW128 antibody, HS1 antibody, KCIP-1 antibody, YWHAA antibody, 1300003C17Rik antibody, wu:fb22g04 antibody, wu:fr86a12 antibody, ywhab antibody, ywhab2 antibody, zgc:64092 antibody, 14-3-3beta antibody, fb80c08 antibody, fk41f08 antibody, wu:fb80c08 antibody, wu:fd11d01 antibody, wu:fk41f08 antibody, ywhab1 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a antibody, YWHAB antibody, Ywhab antibody, ywhabb antibody, ywhab.S antibody, ywhab.L antibody, ywhaba antibody
- 背景
- 14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004, Dougherty and Morrison, 2004). The14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking. These functions of 14-3-3 proteins are facilitated by, if not dependent on, its dimeric structure. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation (Woodcock et al., 2003). Anti-Phospho-Ser58 14-3-3 Protein Western blot of rat brainstem lysate showing specific immuno- labeling of the ~29k 14-3-3 protein phosphorylated at Ser58 (Control). The immunolabeling is blocked by the phosphopeptide used as the antigen (Phos-pep) but not by the corresponding dephosphopeptide (not shown).
- 分子量
- '29 kDa
- 基因ID
- 56011
- UniProt
- P35213
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location
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